Homocysteine is an amino acid.


  • Studies have shown that a high level of homocysteine in the blood is related to an increased risk of coronary heart disease, stroke and peripheral vascular disease.
  • Homocysteine is just one risk factor for cardiovascular disease and any type of nutritional approach to reducing this risk should consider a person’s overall risk profile.
  • Blood homocysteine levels are strongly influenced by diet, obesity, age as well as by genetic factors.
  • The dietary components with the greatest effects in helping to break down homocysteine, are folic acid and vitamins B6 and B12.
  • Although evidence for the benefit of lowering homocysteine levels is not conclusive, individuals at high risk should be advised to take supplemental folic acid and vitamins B6 and B12.

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